• European Marine Science
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The relationship between classical morphometric measurements (12) and meristic traits (8) was examined in 435 specimens of megrim (214 males, 221 females) caught in the eastern central Adriatic Sea. Total length of all specimens ranged from 9.0 to 34.6 cm. Morphological differences between males and females was not marked. Biometric analysis of the morphometric and meristic traits indicated a homogenous morphology stock of Lepidorhombus whiffiagonis in the eastern central Adriatic Sea. Changes in some morphometric traits obtained in conjunction with an increase in body length showed that smaller specimens have longer standard length, head, pectoral fins and preanal distance than adult specimens. The positive correlation recorded for the maximum body height indicated that the body slightly shortened with megrim growth. The morphometric and meristic traits of megrim from different Mediterranean and northeastern Atlantic areas are mostly in accordance with previously published articles.

Pathological lying is compulsive and impulsive, pervasive conduct of the individual, does not aim to achieve material gain, but sometimes there are also self-defeating quality. A small number of research works on intelligence or personality of people who exhibit pathological lying, because they are not operationalized criteria of disorder and methodology of the test assessment. The aim of this paper is presenting how psychological assessment can respond to a number of important questions: a differential diagnostic dilemma (distinguishing pathological lying of confabulations, delusions beliefs and simulation), what is the amount and structure of intelligence in these subjects, if the person proves neuropsychological deficits that are expected in the prefrontal localization, whether pathological lying beside respondent meets criteria for personality disorder, identifying roles / motives which lie in a dynamic personality, the family system and social environment. The paper outlines the specific psychological tests to be applied in order to respond to these questions and how to harmonize the methods of testing with patients who exhibit pathological lying.

Element concentrations in selected fish species from different trophic levels were analyzed. The following fish species were analyzed: common nase (Chondrostoma nasus), roach (Rutilus rutilus), freshwater bream (Abramis brama), barbel (Barbus barbus), Prussian carp (Carassius gibelio),chub (Squalius cephalus), European perch (Perca fluviatilis), wels catfish (Silurus glanis)and northern pike (Esox lucius). Fish were collected from the Međuvršje Reservoir (West Morava River Basin, western Serbia) during 2012, and samples of liver, muscle and gills were analyzed for As, B, Ba, Cd, Co, Cr, Cu, Fe, Hg, Li, Mn, Mo, Ni, Pb, Sr, and Zn using inductively coupled plasma optical emission spectrometry (ICP-OES). The liver and gills had the highest measured element concentrations, with Cu, Zn, Fe and Sr being the most prominent. The bioaccumulation of metals was species-specific, with the accumulation exhibiting the following trends: Prussian carp > northern pike > freshwater bream > European perch > chub > common nase > barbell > roach > wels catfish; Li>Pb>Zn>Cu>Fe>Ba>Mn>Sr>Cr>As>Mo>Ni>B, in all examined species; for Co, Cd and Hg, the bioaccumulation factor (BAF) was 0. Results of this study point to the tissue-specific differences in element concentrations, and to distinct differences between fish species regarding the accumulation patterns: common nase, with the highest accumulation observed in the liver, and Prussian carp, with the highest accumulation observed in the gills. [Projekat Ministarstva nauke Republike Srbije, br. 173045 i br. 37009]

Topolnitsa Reservoir is located in a region of Bulgaria rich in copper mines where intensive mining has been ongoing for several decades. General data on the ecological status of the reservoir and the effects of metal on fish is relatively scarce. The first aim of the study was to measure the concentrations of six metals (As, Cd, Cu, Ni, Pb and Zn) in water samples and in the gills of European perch (Perca fluviatilis L.). The second objective was to examine gill structure and determine the severity of histological alteration as a result of metal exposure. Surface water and fish gill samples were collected in spring, summer and autumn in 2012 and metal and histological analyses were performed. Metal concentrations in the water samples varied, but only Cu concentrations were determined in all three seasons and they were higher than the maximum permissible levels. The gill metal concentrations were significantly higher (P<0.05) than in the water. Examination of gill structure revealed the presence of proliferative and degenerative changes, as well as changes in the blood vessels. Histological lesions were similar in their severity in all three seasons. This study provides the first information about metal effects on the morphology of European perch gills from Topolnitsa Reservoir. It can be concluded that the metal contamination of the Topolnitsa Reservoir and fish is chronic and that it can negatively affect the structure and function of fish gills. As metals display a tendency to accumulate in fish gills, their effects are expected to become more severe with time, as they affect gill functions.

Osmotic treatment of the fish Carassius gibelio was studied in two osmotic solutions: ternary aqueous solution - S1, and sugar beet molasses - S2, at three solution temperatures of 10, 20 and 30oC, at atmospheric pressure. The aim was to examine the influence of type and concentration of the used hypertonic agent, temperature and immersion time on the water loss, solid gain, dry mater content, aw and content of minerals (Na, K, Ca and Mg). S2 solution has proven to be the best option according to all output variables.[ Projekat Ministarstva nauke Republike Srbije, br. TR 31055]

We studied TOP2A amplification (using FISH methods), and TOP2A and BRCA1 protein overexpression (immunohistochemistry) in four molecular subtypes of breast cancer. Of 53 patients, 32 showed TOP2A and 38 showed BRCA1 overexpression. The highest percentage of TOP2A amplification (47.8%) and deletion (13%) was detected in Luminal B subtypes. Of 11 Luminal B tumors with TOP2A amplification, 9 (81.8%) overexpressed TOP2A. BRCA1 protein overexpression showed significant positive correlation with TOP2A protein expression. BRCA1 and TOP2A proteins exhibited similar patterns of expression in Luminal B and triple-negative breast cancer, suggesting the same prognosis in those patients. [Projekat Ministarstva nauke Republike Srbije, br. 175053]