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91 research outcomes, page 1 of 10

publication . Article . 2013
Subtilomycin: A New Lantibiotic from Bacillus subtilis Strain MMA7 Isolated from the Marine Sponge Haliclona simulans
Open Access
Authors:
Phelan, Robert; Barret, Matthieu; Cotter, Paul; O'Connor, Paula; Chen, Rui; Morrissey, John; Dobson, Alan; O'Gara, Fergal; Barbosa, Teresa;
Persistent Identifiers
doi: 10.3390/md11061878
pmc: PMC3721211
pmid: 23736764
Publisher: MDPI AG
Country: France
Project: SFI | Functional Genomics of a ... (08/RFP/GEN1295), EC | PHARMASEA (312184), EC | MACUMBA (311975), SFI | Systems analysis of modul... (08/RFP/GEN1319), EC | MICRO B3 (287589)
This research was supported in parts by grants awarded to FOG by the Science Foundation of Ireland (08/RFP/GEN1295, 08/RFP/GEN1319, SFI09/RFP/BMT2350); the Department of Agriculture, Fisheries and Food (RSF grants 06-321 and 06-377; FIRM grants 06RDC459 06RDC506 and 08R...
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publication . Other literature type . Article . 2016
Exploiting Interkingdom Interactions for Development of Small-Molecule Inhibitors of Candida albicans Biofilm Formation
Open Access
Authors:
F. Jerry Reen; John P. Phelan; Lorna Gallagher; David Woods; Rachel Shanahan; Rafael Cano; Eoin Ó Muimhneacháin; Gerard P. McGlacken; Fergal O'Gara;
Persistent Identifiers
doi: 10.1128/aac.00190-16
pmc: PMC5038327
pmid: 27458231
handle: 10468/8847
Publisher: American Society for Microbiology
Country: Ireland
Project: EC | INMARE (634486), SFI | Small molecule inhibitors... (13/TIDA/B2625), SFI | Development of small mole... (12/TIDA/B2411), SFI | Next Generation Antibioti... (14/TIDA/2438), SFI | Optimised detection of ke... (12/TIDA/B2405)
ABSTRACT A rapid decline in the development of new antimicrobial therapeutics has coincided with the emergence of new and more aggressive multidrug-resistant pathogens. Pathogens are protected from antibiotic activity by their ability to enter an aggregative biofilm st...
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publication . Article . 2016
Highly branched poly(β-amino ester)s for skin gene therapy
Closed Access
Authors:
Zhou, Dezhong; Gao, Yongsheng; Aied, Ahmed; Cutlar, Lara; Igoucheva, Olga; Newland, Ben; Alexeeve, Vitali; Greiser, Udo; Uitto, Jouni; Wang, Wenxin;
Persistent Identifiers
doi: 10.1016/j.jconrel.2016.06.014
Publisher: Elsevier BV
Project: SFI | In situ formed Skin Subst... (13/IA/1962), SFI | Targeted Drug Delivery of... (15/TIDA/2969), SFI | Bio-reducible highly bran... (15/IFA/3037)
Poly(β-amino ester)s (PAEs) have emerged as a promising class of gene delivery vectors with performances that can even be compared to viruses. However, all of the transfection studies (over 2350 PAEs) have been limited to linear poly(β-amino ester)s (LPAEs) despite incr...
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publication . Article . 2019
Quorum Sensing Signaling Alters Virulence Potential and Population Dynamics in Complex Microbiome-Host Interactomes
Open Access English
Authors:
F. Jerry Reen; F. Jerry Reen; José A. Gutiérrez-Barranquero; Ronan R. McCarthy; David F. Woods; Sara Scarciglia; Claire Adams; Kristian Fog Nielsen; Lone Gram; Fergal O’Gara; ...
Persistent Identifiers
doi: 10.3389/fmicb.2019.02131
pmc: PMC6749037
pmid: 31572336
handle: 10468/8751
Publisher: Frontiers Media S.A.
Countries: Denmark, United Kingdom, Ireland
Project: EC | INMARE (634486), SFI | Pre-clinical testing of n... (15/TIDA/2977)
Despite the discovery of the first N-acyl homoserine lactone (AHL) based quorum sensing (QS) in the marine environment, relatively little is known about the abundance, nature and diversity of AHL QS systems in this diverse ecosystem. Establishing the prevalence and dive...
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publication . Article . Other literature type . 2019
Differential N-end Rule Degradation of RIN4/NOI Fragments Generated by the AvrRpt2 Effector Protease
Open Access
Authors:
Goslin, Kevin; Eschen-Lippold, Lennart; Naumann, Christin; Linster, Eric; Sorel, Maud; Klecker, Maria; de Marchi, Rémi; Kind, Anne; Wirtz, Markus; Lee, Justin; ...
Persistent Identifiers
doi: 10.1104/pp.19.00251 , 10.1101/583054
pmc: PMC6670102
pmid: 31227619
Publisher: American Society of Plant Biologists (ASPB)
Country: Ireland
Project: SFI | Regulation of Plant Immun... (13/IA/1870)
AbstractThe protein RPM1-INTERACTING PROTEIN4 (RIN4) is a central regulator of both layers of plant immunity systems, the so-called pattern-triggered immunity (PTI) and effector-triggered immunity (ETI). RIN4 is targeted by several effectors, including thePseudomonas sy...
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publication . Article . 2014
Evaluating langmuir turbulence parameterizations in the ocean surface boundary layer
Open Access
Authors:
Graig Sutherland; Kai Håkon Christensen; Brian Ward;
Persistent Identifiers
doi: 10.1002/2013jc009537
Publisher: Wiley-Blackwell
Country: Ireland
Project: EC | CARBOCHANGE (264879), SFI | Development of a Greenhou... (08/US/I1455)
It is expected that surface gravity waves play an important role in the dynamics of the ocean surface boundary layer (OSBL), quantified with the turbulent Langmuir number (La-root u(*)/u(s0), where u(*) and u(s0) are the friction velocity and surface Stokes drift, respe...
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publication . Article . 2020
The Slab Puzzle of the Alpine‐Mediterranean Region: Insights from a new, High‐Resolution, Shear‐Wave Velocity Model of the Upper Mantle
Open Access
Authors:
Amr El-Sharkawy; Thomas Meier; Sergei Lebedev; Jan H. Behrmann; Mona Hamada; Luigia Cristiano; Christian Weidle; Daniel Köhn;
Persistent Identifiers
doi: 10.1029/2020gc008993
Publisher: AGU (American Geophysical Union)
Country: Germany
Project: SFI | Irish Centre for Research... (13/RC/2092)
Mediterranean tectonics since the Lower Cretaceous has been characterized by a multiphase subduction and collision history with temporally and spatially variable, small ‐ scale plate con ﬁ gurations. A new shear wave velocity model of the Mediterranean upper mantle (MeR...
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publication . Article . 2017
Visible-light photooxygenation of α-terpinene in a falling film microreactor
Closed Access
Authors:
Oksana Shvydkiv; Klaus Jähnisch; Norbert Steinfeldt; Alexander Yavorskyy; Michael Oelgemöller;
Persistent Identifiers
doi: 10.1016/j.cattod.2017.11.009
Publisher: Elsevier BV
Project: SFI | MicroPhotochemistry - a n... (07/RFP/CHEF817), ARC | Linkage Infrastructure, E... (LE150100049), ARC | Development of microflow ... (DP130100794)
Abstract The photooxygenation of α-terpinene was investigated in a falling film microreactor. The formation of microfilms and the flow operation allowed for a safe and controllable production of the bioactive endoperoxide ascaridole. Stepwise investigation of the proces...
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publication . Article . 2017
Metagenomic Approaches to Assess Bacteriophages in Various Environmental Niches
Open Access English
Authors:
Stephen Hayes; Jennifer Mahony; Arjen Nauta; Douwe van Sinderen;
Persistent Identifiers
doi: 10.3390/v9060127
pmc: PMC5490804
pmid: 28538703
handle: 10468/4104
Publisher: MDPI
Country: Ireland
Project: SFI | Phage-host interactome of... (15/SIRG/3430), SFI | Functional analysis of th... (13/IA/1953)
Bacteriophages are ubiquitous and numerous parasites of bacteria and play a critical evolutionary role in virtually every ecosystem, yet our understanding of the extent of the diversity and role of phages remains inadequate for many ecological niches, particularly in ca...
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publication . Article . 2015
High-strength thermoplastic bonding for multi-channel, multi-layer lab-on-chip devices for ocean and environmental applications
Open Access
Authors:
Sun, D.; Tweedie, M.; Gajula, D. R.; Ward, B.; Maguire, P. D.;
Persistent Identifiers
doi: 10.1007/s10404-015-1620-2
Publisher: Springer Science and Business Media LLC
Countries: United Kingdom, Ireland
Project: SFI | Development of a Micro-Ro... (09/US/I1758)
A solvent vapour thermoplastic bonding process is reported which provides high-strength bonding of PMMA over a large area for multi-channel and multi-layer microfluidic devices with shallow high-resolution channel features. The bond process utilises a low-temperature va...
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91 research outcomes, page 1 of 10

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Subtilomycin: A New Lantibiotic from Bacillus subtilis Strain MMA7 Isolated from the Marine Sponge Haliclona simulans

Exploiting Interkingdom Interactions for Development of Small-Molecule Inhibitors of Candida albicans Biofilm Formation

Highly branched poly(β-amino ester)s for skin gene therapy

Quorum Sensing Signaling Alters Virulence Potential and Population Dynamics in Complex Microbiome-Host Interactomes

Differential N-end Rule Degradation of RIN4/NOI Fragments Generated by the AvrRpt2 Effector Protease

Evaluating langmuir turbulence parameterizations in the ocean surface boundary layer

The Slab Puzzle of the Alpine‐Mediterranean Region: Insights from a new, High‐Resolution, Shear‐Wave Velocity Model of the Upper Mantle

Visible-light photooxygenation of α-terpinene in a falling film microreactor

Metagenomic Approaches to Assess Bacteriophages in Various Environmental Niches

High-strength thermoplastic bonding for multi-channel, multi-layer lab-on-chip devices for ocean and environmental applications