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519 research outcomes, page 1 of 52
  • publication . Other literature type . Article . 2020
    Open Access English
    Authors:
    Christophe Labriere; Vijayaragavan Elumalai; Jannie Staffansson; Gunnar Cervin; Tiffany Le Norcy; Hugo Denardou; Karine Réhel; Lindon W. K. Moodie; Claire Hellio; Henrik Pavia; ...
    Persistent Identifiers
    Publisher: HAL CCSD
    Countries: France, Norway

    Stationary and slow-moving marine organisms regularly employ a natural product chemical defense to prevent being colonized by marine micro- and macroorganisms. While these natural antifoulants can be structurally diverse, they often display highly conserved chemistries ...

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  • publication . Article . 2020
    Open Access English
    Authors:
    Cabral, Lília I. L.; Pomel, Sébastien; Cojean, Sandrine; Amado, Patrícia S. M.; Loiseau, Philippe M.; Cristiano, Maria L. S.;
    Publisher: MDPI
    Country: Portugal
    Project: FCT | PTDC/MAR-BIO/4132/2014 (PTDC/MAR-BIO/4132/2014), FCT | UID/Multi/04326/2019 (UID/Multi/04326/2019), FCT | SFRH/BD/130407/2017 (SFRH/BD/130407/2017)

    A chemically diverse range of novel tetraoxanes was synthesized and evaluated in vitro against intramacrophage amastigote forms of Leishmania donovani. All 15 tested tetraoxanes displayed activity, with IC50 values ranging from 2 to 45 µm. The most active tetraoxane, co...

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  • publication . Article . 2019
    Open Access English
    Authors:
    Chakraborty, Gurudas; Balinin, Konstantin; Portale, Giuseppe; Loznik, Mark; Polushkin, Evgeny; Weil, Tanja; Herrmann, Andreas;
    Country: Netherlands
    Project: EC | SUPRABIOTICS (694610)

    Chemically modified nucleic acids have long served as a very important class of bio-hybrid structures. In particular, the modification with PEG has advanced the scope and performance of oligonucleotides in materials science, catalysis and therapeutics. Most of the appli...

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  • publication . Article . 2020
    Open Access English
    Authors:
    Dorothy A Okoth; Joachim J. Hug; Ronald Garcia; Cathrin Spröer; Jörg Overmann; Rolf Müller;
    Persistent Identifiers
    Publisher: MDPI AG
    Country: Germany

    nucleoside hybrid natural products remains elusive, we investigated secondary metabolomes and genomes of several 2‑hydroxysorangiadenosine-producing myxobacteria. We report the isolation and full structure elucidation of 2‑hydroxysorangiadenosine and its cytotoxic and a...

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  • publication . Article . 2019
    Open Access English
    Authors:
    Matos, Cristina P.; Addis, Yemataw; Nunes, Patrique; Barroso, Sónia; Alho, Irina; Martins, Marta; Matos, António P.A.; Marques, Fernanda; Cavaco, Isabel; Costa Pessoa, João; ...
    Persistent Identifiers
    Publisher: Elsevier
    Country: Portugal
    Project: FCT | UID/Multi/04349/2013 (UID/Multi/04349/2013), FCT | UID/QUI/00100/2013 (UID/QUI/00100/2013)

    Zinc(II) complexes bearing N-salicylideneglycinate (Sal-Gly) and 1,10-phenanthroline (phen) or phenanthroline derivatives [NN= 5-chloro-1,10-phenanthroline, 5-amine-1,10-phenanthroline (amphen), 4,7-diphenyl-1,10-phenanthroline (Bphen) and 5,6-epoxy-5,6-dihydro-1,10-phe...

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  • publication . Article . 2016
    Open Access
    Authors:
    Sara Gomes, Ana; Brandão, Pedro; Sofia Garcia Fernandes, Carla; Ramos Pinto Correia da Silva, Marta; Emília da Silva Pereira de Sousa, Maria; Maria de Magalhães Pinto, Madalena;
    Persistent Identifiers
    Publisher: Bentham Science Publishers Ltd.
    Country: Portugal
    Project: FCT | UID/Multi/04423/2013 (UID/Multi/04423/2013), EC | BLUEandGREEN (692419)

    Xanthone derivatives have been described as compounds with a privileged scaffold exhibiting diverse biological/pharmacological activities, what directed the interest to pursue the development of these derivatives into drug candidates. Nevertheless, to achieve this purpo...

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  • publication . Article . 2017
    Open Access
    Authors:
    Patrícia Neves; Lucie S. Nogueira; Ana C. Gomes; Tânia S. M. Oliveira; André D. Lopes; Anabela A. Valente; Isabel S. Gonçalves; Martyn Pillinger;
    Persistent Identifiers
    Publisher: Wiley
    Country: Portugal
    Project: FCT | UID/CTM/50011/2013 (UID/CTM/50011/2013)

    The chemistry and catalytic performance of the dichlorido complex [MoO2Cl2(pbim)] (1) [pbim = 2-(2-pyridyl)benzimidazole] in the epoxidation of olefins is reported. Complex 1 acts as a precatalyst and is more effective with tert-butyl-hydroperoxide (TBHP) as the oxidant...

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  • publication . Article . Preprint . 2019
    Open Access
    Authors:
    Braga, Daniel; Last, Daniel; Hasan, Mahmudul; Guo, Huijuan; Leichnitz, Daniel; Uzum, Zerrin; Richter, Ingrid; Schalk, Felix; Beemelmanns, Christine; Hertweck, Christian; ...
    Publisher: American Chemical Society (ACS)
    Project: EC | FUNBIOSIS (794343)

    AbstractCoenzyme F420is a specialized redox cofactor with a highly negative redox potential. It supports biochemical processes like methanogenesis, degradation of xenobiotics or the biosynthesis of antibiotics. Although well-studied in methanogenic archaea and actinobac...

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  • publication . Article . 2019
    Open Access
    Authors:
    Romeol Romain Koagne; Gabin Thierry M. Bitchagno; Serge A.T. Fobofou; Ingrid Simo Konga; Jean De Dieu Tamokou; Ludger A. Wessjohann; Pierre Tane;
    Persistent Identifiers
    Publisher: SAGE Publications

    Rothmannia talbotii, a hitherto chemically unexplored medicinal plant, is used in the Western Region of Cameroon to relieve fever. In our ongoing search for bioactive compounds from Cameroonian medicinal plants, a previously undescribed compound rothtalazepane (1), alo...

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  • publication . Article . 2016
    Open Access English
    Authors:
    Manuel Aureliano; C. André Ohlin; Michele O. Vieira; M. Paula M. Marques; William H. Casey; Luís A. E. Batista de Carvalho;
    Persistent Identifiers
    Countries: United States, Portugal
    Project: FCT | UID/Multi/00070/2013 (UID/Multi/00070/2013), NSF | Center for Sustainable Ma... (1102637)

    The decaniobate ion, (Nb10 = [Nb10O28](6-)) being isoelectronic and isostructural with the decavanadate ion (V10 = [V10O28](6-)), but chemically and electrochemically more inert, has been useful in advancing the understanding of V10 toxicology and pharmacological activi...

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519 research outcomes, page 1 of 52