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2,964 research outcomes, page 1 of 297

publication . Article . 2019
Diet-related selectivity of macroplastic ingestion in green turtles (Chelonia mydas) in the eastern Mediterranean
Open Access English
Authors:
Duncan, Emily M.; Arrowsmith, Jessica A.; Bain, Charlotte E.; Bowdery, Hannah; Broderick, Annette C.; Chalmers, Tierney; Fuller, Wayne J.; Galloway, Tamara S.; Lee, Jonathon H.; Lindeque, Penelope K.; ...
Persistent Identifiers
doi: 10.1038/s41598-019-48086-4
pmc: PMC6688982
pmid: 31399637
Publisher: Nature Publishing Group UK
Project: UKRI | Bioavailability and biolo... (NE/L007010/1), EC | CLEANSEA (308370)
Abstract Understanding the drivers of key interactions between marine vertebrates and plastic pollution is now considered a research priority. Sea turtles are primarily visual predators, with the ability to discriminate according to colour and shape; therefore these fac...
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publication . Article . Preprint . 2020
Assessment of Fatty Acid Desaturase (Fads2) Structure-Function Properties in Fish in the Context of Environmental Adaptations and as a Target for Genetic Engineering
Open Access English
Authors:
Zuzana Bláhová; Thomas Nelson Harvey; Martin Pšenička; Jan Mráz;
Persistent Identifiers
doi: 10.20944/preprints202001.0330.v1 , 10.3390/biom10020206
pmc: PMC7072455
pmid: 32023831
handle: 11250/2687332
Publisher: MDPI AG
Country: Norway
Fatty acid desaturase 2 (Fads2) is the key enzyme of long-chain polyunsaturated fatty acid (LC-PUFA) biosynthesis. Endogenous production of these biomolecules in vertebrates, if present, is insufficient to meet demand. Hence, LC-PUFA are considered as conditionally esse...
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publication . Article . 2018
Pallidal Stimulation Modulates Pedunculopontine Nuclei in Parkinson’s Disease
Open Access English
Authors:
Imke Galazky; Christian Kluge; Friedhelm C. Schmitt; Klaus Kopitzki; Tino Zaehle; Jürgen Voges; Lars Büntjen; Andreas Kupsch; Hermann Hinrichs;
Persistent Identifiers
doi: 10.3390/brainsci8070117
pmc: PMC6071240
pmid: 29941788
Publisher: MDPI
s disease. In particular, we compared the local field potentials from the pedunculopontine nucleus region at rest and during deep brain stimulation of the globus pallidus internus. Results: At rest, the spectrum of local field potentials in the globus pallidus internus ...
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publication . Article . 2021
A novel role of Zebrafish TMEM33 in negative regulation of interferon production by two distinct mechanisms
Open Access
Authors:
Long-Feng Lu; Can Zhang; Zhuo-Cong Li; Xiao-Yu Zhou; Jing-Yu Jiang; Dan-Dan Chen; Yong-An Zhang; Feng Xiong; Fang Zhou; Shun Li;
Persistent Identifiers
doi: 10.1371/journal.ppat.1009317
pmc: PMC7891750
pmid: 33600488
Publisher: Public Library of Science (PLoS)
The transmembrane protein 33 (TMEM33) was originally identified as an endoplasmic reticulum (ER) protein that influences the tubular structure of the ER and modulates intracellular calcium homeostasis. However, the role of TMEM33 in antiviral immunity in vertebrates has...
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publication . Article . 2017
The effect of PD-L1 testing on the cost-effectiveness and economic impact of immune checkpoint inhibitors for the second-line treatment of NSCLC
Open Access
Authors:
P.N. Aguiar; L.A. Perry; J. Penny-Dimri; H. Babiker; H. Tadokoro; R.A. de Mello; G.L. Lopes;
Persistent Identifiers
doi: 10.1093/annonc/mdx305 , 10.1093/annonc/mdx478
handle: 10400.1/11907
Publisher: Elsevier BV
Countries: Brazil, Portugal
Made available in DSpace on 2019-08-19T11:48:40Z (GMT). No. of bitstreams: 0 Previous issue date: 2017 Background: Immune checkpoint inhibitors improve outcomes compared with chemotherapy in lung cancer. Tumor PD-L1 receptor expression is being studied as a predictive b...
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publication . Article . Other literature type . 2019
Epidemiological surveillance of schistosomiasis outbreak in Corsica (France): Are animal reservoir hosts implicated in local transmission?
Open Access English
Authors:
Oleaga, Ana; Rey, Olivier; Polack, Bruno; Grech-Angelini, Sébastien; Quilichini, Yann; Pérez-Sánchez, Ricardo; Boireau, Pascal; Mulero, Stephen; Brunet, Aimé; Rognon, Anne; ...
Persistent Identifiers
doi: 10.1371/journal.pntd.0007543
handle: 10261/185993
pmc: PMC6611637
pmid: 31233502
Publisher: HAL CCSD
Countries: Spain, France
Environmental and anthropogenic changes are expected to promote emergence and spread of pathogens worldwide. Since 2013, human urogenital schistosomiasis is established in Corsica island (France). Schistosomiasis is a parasitic disease affecting both humans and animals....
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publication . Article . 2021
Riociguat treatment in patients with chronic thromboembolic pulmonary hypertension: Final safety data from the EXPERT registry
Open Access English
Authors:
Ghofrani, H. -A.; Gomez Sanchez, M. -A.; Humbert, M.; Pittrow, D.; Simonneau, G.; Gall, H.; Grunig, E.; Klose, H.; Halank, M.; Langleben, D.; ...
Persistent Identifiers
doi: 10.1016/j.rmed.2020.106220
handle: 2268/259592
Publisher: Elsevier B.V.
Countries: Belgium, Netherlands, Turkey, Netherlands, Spain, Belgium, Italy
Objective: The soluble guanylate cyclase stimulator riociguat is approved for the treatment of adult patients with pulmonary arterial hypertension (PAH) and inoperable or persistent/recurrent chronic thromboembolic pulmonary hypertension (CTEPH) following Phase 3 random...
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publication . Article . 2020
High glucose distinctively regulates Ca ²⁺ influx in cytotoxic T lymphocytes upon target recognition and thapsigargin stimulation
Open Access
Authors:
Huajiao Zou; Wenjuan Yang; Gertrud Schwär; Renping Zhao; Dalia Alansary; Deling Yin; Eva C. Schwarz; Barbara A. Niemeyer; Bin Qu;
Persistent Identifiers
doi: 10.1002/eji.202048577
Publisher: Wiley
In CTLs: High glucose-culture enhances thapsigargin-induced SOCE but decreases target recognition-induced Ca2+ influx. High glucose-culture regulates expression of ORAIs and STIMs without affecting glucose uptake. More high glucose-cultured CTLs are prone to necrosis af...
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publication . Other literature type . Article . 2017
Oral epithelial cells orchestrate innate type 17 responses to Candida albicans through the virulence factor candidalysin
Open Access
Authors:
Verma, Akash H.; Richardson, Jonathan P.; Zhou, Chunsheng; Coleman, Bianca M.; Moyes, David L.; Ho, Jemima; Huppler, Anna R.; Ramani, Kritika; McGeachy, Mandy J.; Mufazalov, Ilgiz A.; ...
Persistent Identifiers
doi: 10.1126/sciimmunol.aam8834
pmc: PMC5881387
pmid: 29101209
Publisher: American Association for the Advancement of Science (AAAS)
Country: United Kingdom
Candida albicans is a dimorphic commensal fungus that causes severe oral infections in immunodeficient patients. Invasion of C. albicans hyphae into oral epithelium is an essential virulence trait. Interleukin-17 (IL-17) signaling is required for both innate and adaptiv...
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publication . Article . 2020
Prostate cancer management: long-term beliefs, epidemic developments in the early twenty-first century and 3PM dimensional solutions
Open Access English
Authors:
Radek Kucera; Ladislav Pecen; Ondrej Topolcan; Anshu Raj Dahal; Vincenzo Costigliola; Frank A. Giordano; Olga Golubnitschaja;
Persistent Identifiers
doi: 10.1007/s13167-020-00214-1
pmc: PMC7429585
pmid: 32843909
Publisher: Springer International Publishing
AbstractIn the early twenty-first century, societies around the world are facing the paradoxal epidemic development of PCa as a non-communicable disease. PCa is the most frequently diagnosed cancer for men in several countries such as the USA. Permanently improving diag...
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Diet-related selectivity of macroplastic ingestion in green turtles (Chelonia mydas) in the eastern Mediterranean

Assessment of Fatty Acid Desaturase (Fads2) Structure-Function Properties in Fish in the Context of Environmental Adaptations and as a Target for Genetic Engineering

Pallidal Stimulation Modulates Pedunculopontine Nuclei in Parkinson’s Disease

A novel role of Zebrafish TMEM33 in negative regulation of interferon production by two distinct mechanisms

The effect of PD-L1 testing on the cost-effectiveness and economic impact of immune checkpoint inhibitors for the second-line treatment of NSCLC

Epidemiological surveillance of schistosomiasis outbreak in Corsica (France): Are animal reservoir hosts implicated in local transmission?

Riociguat treatment in patients with chronic thromboembolic pulmonary hypertension: Final safety data from the EXPERT registry

High glucose distinctively regulates Ca ²⁺ influx in cytotoxic T lymphocytes upon target recognition and thapsigargin stimulation

Oral epithelial cells orchestrate innate type 17 responses to Candida albicans through the virulence factor candidalysin

Prostate cancer management: long-term beliefs, epidemic developments in the early twenty-first century and 3PM dimensional solutions