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727 research outcomes, page 1 of 73
  • publication . Article . 2017
    Open Access
    Authors:
    P.N. Aguiar; L.A. Perry; J. Penny-Dimri; H. Babiker; H. Tadokoro; R.A. de Mello; G.L. Lopes;
    Publisher: Elsevier BV
    Countries: Brazil, Portugal

    Made available in DSpace on 2019-08-19T11:48:40Z (GMT). No. of bitstreams: 0 Previous issue date: 2017 Background: Immune checkpoint inhibitors improve outcomes compared with chemotherapy in lung cancer. Tumor PD-L1 receptor expression is being studied as a predictive b...

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  • publication . Article . 2020
    Open Access English
    Authors:
    Radek Kucera; Ladislav Pecen; Ondrej Topolcan; Anshu Raj Dahal; Vincenzo Costigliola; Frank A. Giordano; Olga Golubnitschaja;
    Persistent Identifiers
    Publisher: Springer International Publishing

    AbstractIn the early twenty-first century, societies around the world are facing the paradoxal epidemic development of PCa as a non-communicable disease. PCa is the most frequently diagnosed cancer for men in several countries such as the USA. Permanently improving diag...

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  • publication . Article . Preprint . 2020
    Open Access
    Authors:
    Kumuditha M. Weerakoon-Ratnayake; Swarnagowri Vaidyanathan; Nicholas Larkey; Kavya Dathathreya; Mengjia Hu; Jilsha Jose; Shalee Mog; Keith J. August; Andrew K. Godwin; Mateusz L. Hupert; ...
    Publisher: MDPI AG
    Project: NIH | Increased sensitivity of ... (1R44CA224848-01A1), NIH | Biotechnology Resource Ce... (1P41EB020594-01), NIH | Cancer Center Support Gra... (3P30CA168524-07S2)

    The role of circulating plasma cells (CPCs) and circulating leukemic cells (CLCs) as biomarkers for several blood cancers, such as multiple myeloma and leukemia, respectively, have recently been reported. These markers can be attractive due to the minimally invasive nat...

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  • publication . Article . 2019
    Open Access English
    Authors:
    Huang, Sixia; Nong, Lin; Liang, Li; Zheng, Yalin; Wang, Wei; Liu, Jumei; Li, Dong; Li, Xin; Wang, Ying; Zhang, Bo; ...
    Persistent Identifiers
    Publisher: John Wiley and Sons Inc.

    Abstract The expression of programmed cell death ligand 1 (PD‐L1) is a biomarker for immunotherapy, but approved detection method is absent in diffuse large B‐cell lymphoma (DLBCL). Here, we performed three methods including immunohistochemistry (IHC) (clone SP263 and S...

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  • publication . Article . 2020
    Open Access English
    Authors:
    Filipe V. Jacinto; Wolfgang Link; Bibiana I. Ferreira;
    Countries: Spain, Portugal
    Project: FCT | UID/BIM/04773/2013 (UID/BIM/04773/2013), EC | TRIBBLES (748585)

    The recent development of the CRISPR/Cas9 system as an efficient and accessible programmable genome‐editing tool has revolutionized basic science research. CRISPR/Cas9 system‐based technologies have armed researchers with new powerful tools to unveil the impact of genet...

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  • The cellular glycocalyx of vertebrates is frequently decorated with sialic acid residues. These sialylated structures are recognized by sialic acid-binding immunoglobulin-type lectins (Siglecs) of immune cells, which modulate their responsiveness. Fifteen Siglecs are kn...

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  • publication . Article . 2020
    Open Access English
    Authors:
    Louise van der Weyden; Thomas Brenn; E. Elizabeth Patton; Geoffrey A. Wood; David J. Adams;
    Country: United Kingdom
    Project: EC | ZF-MEL-CHEMBIO (648489)

    Abstract In contrast to other cancer types, melanoma incidence has been increasing over the last 50 years, and while it still represents less than 5% of all cutaneous malignancies, melanoma accounts for the majority of skin cancer deaths, due to its propensity to metast...

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  • publication . Article . 2021
    Open Access English
    Authors:
    M. Noia; Francisco Fontenla-Iglesias; A. Valle; V. Blanco-Abad; José Leiro; Jesús Lamas;
    Persistent Identifiers
    Publisher: Elsevier
    Country: Spain
    Project: EC | ParaFishControl (634429)

    We have completed the characterization of the turbot (Scophthalmus maximus) myeloperoxidase (mpx) gene and protein, which we partially described in a previous study. The turbot mpx gene has 15 exons that encode a protein of 767 aa, with a signal peptide, propeptide and ...

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  • publication . Article . 2017
    Open Access
    Authors:
    Harbord, Marcus; Eliakim, Rami; Bettenworth, Dominik; Karmiris, Konstantinos; Katsanos, Konstantinos; Kopylov, Uri; Kucharzik, Torsten; Molnar, Tamas; Raine, Tim; Sebastian, Shaji; ...
    Persistent Identifiers
    Publisher: Oxford University Press (OUP)
    Country: Portugal

    info:eu-repo/semantics/publishedVersion

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  • publication . Article . 2019
    Open Access English
    Authors:
    Dreher, Dorothée; Baldermann, Susanne; Schreiner, Monika; Hause, Bettina;
    Persistent Identifiers
    Publisher: Elsevier
    Country: Germany

    Plants are in permanent contact with various microorganisms and are always impacted by them. To better understand the first steps of a plant’s recognition of soil-borne microorganisms, the early release of volatile organic compounds (VOCs) emitted from roots of Medicago...

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727 research outcomes, page 1 of 73