WInSiC4AP core objective is to contribute in developing reliable technology bricks for efficient and cost-effective applications addressing social challenges and market segments where Europe is a recognized global leader as well as automotive, avionics, railway and defence. WInSiC4AP approach is to rely on the strength of vertical integration allowing optimization, technologies fitting application requirements, developing the full ecosystem and approach relevant issues as reliability in the full scope. That enhances the competitiveness of EU- Industries as well as TIER1 and TIER2 down to the value chain in a market context where other countries today, such as the USA or Japan, are advancing and new players accessing SiC enter in the market. New topologies and architecture will be developed for targeted application simulating operational environment, at laboratory level, driving the needed and still missed technologies, components and demonstrators to fill the gap between current state of the art and the very high demanding specifications. WInSiC4AP framework has been built so that companies working in different domains (i.e. automotive car maker and TIER1-2 and avionics, railway and defence TIER1-TIER2) and in the vertical value chain (semiconductor suppliers, companies manufacturing inductors and capacitors) as well as academic entities and laboratories will collaborate to co-design solutions, solve problems and exchange know-how, such that unforeseen results may also emerge. WInSiC4AP will be supported with synergy between ECSEL JU and ESI funding enabling complementary activities with relevant economic and social impact envisage in a less development region of Union.

Multidrug resistance of Mycobacterium tuberculosis is declared a serious global threat by the World Health Organization. Our project aims at developing a comprehensive model of molecular mechanisms responsible for antimicrobial drug resistance of tuberculosis. Isoniazid is the main drug used for TB treatment, because it interacts with the bacterial catalase that leads to the bacterial death. The library of isoniazid resistant strains (over 100 different strains) will be used as experimental basis for building theoretical and computational models of the molecular processes leading to drug resistance of mutated bacteria. The model will be used for suggesting effective treatment targeting these mechanisms and overcoming the resistance. AMR-TB RISE will be used to utilise the expertise of highly specialised research groups of biologists, clinicians, biochemists, physicists, computer engineers, and mathematicians allowing the researches from these groups to work in multiple laboratories of the Consortium all over the world. Particular attention will be given to training the next generation of young researcher and forming tightly interconnected, long term collaboration devoted to solving the pressing global problem of antimicrobial resistance not only in TB, but in a wide spectrum of diseases.

The GALATEO (Good Attitudes for Life in Assyrian Times: Etiquette and Observance of Norms in Male and Female Groups) project aims to understand anew the importance of etiquette in late Assyrian society (10th–7th century BCE) and to investigate through a multidisciplinary approach the extent to which etiquette influenced the subsequent cultures of the Middle East. As a showcase of the project, the creation of an open source Atlas will be delivered, which is conceived as an open repository, in which the addition of new references to delineate the manners of a given culture can contribute to the understanding of etiquette, from the ancient to the modern Middle East. GALATEO develops and works through an adaptable sociological and anthropological theoretical model for the study of etiquette in the ancient Middle East. To this end, the sociological perspective will explore the way that correct behaviour in Assyrian society was codified and imposed during meetings, both religious and lay, in variously political, economic, and convivial settings. In this way it will be investigated how etiquette becomes a means for both men and women to display their social status and gender balance. The anthropological perspective will examine the etiquette of hygiene, especially concerning the practices of proper handwashing, body washing, facial cleanliness, and bodily purification from a religious point of view, the intention of which was to avoid the transmission of disease, such as sex and bodily pollutions, as well as the admission of evil spirits. This analysis will show how the extent to which hygiene plays a role in assigning order and integrity to a culture or group. Being adaptable, this model will pave the way for emerging new perspectives on understanding the social history of a number of cultures of the ancient Middle East in light of etiquette, to better understand contemporaneous ones.

The peculiar behaviour of liquid and supercooled water has been baffling science for at least 236 years and is still seen as a major challenge facing chemistry today (Whitesides & Deutch, Nature 469, 21 (2011)). It was suggested that such strange behaviour might be caused by thermodynamic transitions, possibly even a second critical point. This second critical point would terminate a coexistence line between low- and high-density amorphous phases of water. Unfortunately, this second critical point (if it exists) and the associated polyamorphic liquid-liquid transition is difficult to study as it is thought to lie below the homogeneous nucleation temperature in a region known as "no man's land" (Angell, Science 319, 582 (2008)). In recent preliminary femtosecond optical Kerr-effect spectroscopy experiments, we have shown that water in concentrated eutectic solutions forms nanometre scale pools in which it retains many if not most of its bulk liquid characteristics. Most importantly, such solutions can be cooled to below 200 K without crystallisation (typically forming a glass at lower temperatures) allowing one to explore "no man's land" in detail for the first time. Preliminary experiments combining femtosecond spectroscopy with NMR diffusion measurements have shown that water in these pools undergoes a liquid-liquid transition as predicted for bulk water. Hence, it is proposed to use such nanopools as nanometre scale laboratories for the study of liquid and glassy water. A wide-ranging international collaboration has been set up to be able to study different critical aspects of the structure and dynamics of water. This includes cryogenic viscosity measurements, large dynamic-range (femtosecond to millisecond) optical Kerr-effect experiments, pulsed field gradient NMR, dielectric relaxation spectroscopy, terahertz time-domain spectroscopy, infrared pump-probe spectroscopy, and two-dimensional infrared spectroscopy. To ensure maximum impact of the experimental work, it is critical to have strong ties with experts in the theory and simulation of water and its thermodynamic behaviour. We have arranged collaboration with two international theory groups covering different aspects of the proposed work. Although the proposed research is relatively fundamental in nature, it will have impact as described in more detail elsewhere. The research addresses EPSRC priorities in nanoscience (supramolecular structures in liquids), energy (proton transport and liquid structuring in electrolytes for batteries and fuel cells), life sciences (the role of water in and on biomolecules), and the chemistry-chemical engineering interface (the role of the structuring of water in crystal nucleation). Our strong links with theory collaborators will ensure that fundamental insights will indeed propagate to the 'users' of such information. The close working relationship between the PI and CI has made Glasgow a centre of excellence in advanced femtosecond spectroscopy. This project exploits this expertise and international collaborations to immerse PDRAs and PGRSs in internationally leading research using state-of-the-art previously funded equipment.