The ambition of the CONNECARE consortium is to co-design, develop, deploy, and evaluate a novel smart, adaptive integrated care system for chronic care management. This will save European healthcare organisations huge sums whilst improving patient outcomes. The consortium contains all the necessary partners to ensure success. Based on the concept of 4P medicine, CONNECARE will provide decision support for the adaptive management of personalised clinical pathways and will deliver tools to monitor patients’ activities and status, thus empowering them and providing them with recommendations to self-manage their condition, resulting in substantial improvements in their quality of life. The three dimensions underpinning the required proposed paradigm shift are: 1. Organisational: making health and social care systems interoperable, promoting collaboration among care settings, and moving from institutional reactive care to a home-based preventive model. 2. Care and social services: addressing health risk prediction by combining already operational population-based tools with a patient-based five-dimension scoring strategy consisting of i) screening, ii) risk stratification, iii) mapping, iv) intervention, and v) surveillance. 3. Technological: delivering a CONNECARE system which leverages existing assets from partners to offer smart Adaptive Case Management, self-management and 3-level monitoring features, fully integrated with management systems in place. An iterative patient-centred co-design process will ensure a progressive refinement of model and tools, providing foundations for adoption and transferability. In addition, clinical trials will be held in three leading-light regions in integrated care uptake –Catalonia, Israel, and Groningen – to evidence improvements in outcomes and efficiency. Consortium members are active in the EIP AHA B3 Action Group; transfer of results to relevant stakeholders across Europe, beyond the stakeholders in CONNECARE, is guaranteed.

Trillium-II steps forward with an outstanding consortium to further advance global Electronic Health Record (EHR) interoperability. Activities surrounding the International Patient Summary (IPS) standards can nurture digital health innovation, lower trade barriers, and advance patient safety & trust, bridging the gap between strategic intent and capability for action by Standards Development Organization (SDOs) striving for interoperability, quality, and safety through standards adoption. Trillium-II builds on the vibrant community of Trillium Bridge to: (a) Improve international interoperability of eHealth Systems in US, in Europe and globally (b) Accelerate establishment of interoperability standards in eHealth with validated open source interoperability assets and sharing lessons learned with SDOs (c) Facilitate secure, seamless patient summary sharing offering clarity and oversight. Trillium-II aims to bridge, harmonize, evaluate existing patient summary initiatives and guide emerging ones, leading the way toward one IPS standard by establishing a global community fostering the practice of digital health innovation with robust widely-used interoperability standards and joint pilots. Trillium-II objectives are measurable, realistic and achievable objectives: • Highlight the social value of IPS standards. • Bridge IPS initiatives with validated interoperability assets, sharing lessons learned with SDOs • Contribute to IPS Standards Governance under the JIC • Develop, Collect and Assess IPS Learning resources • Engage mobile Health companies and app developers with IPS standards • Foster innovation & inform health policy sharing IPS. Trillium-II will work with the workforce action, EU and US SDO platforms, large scale eHealth deployments, and emergency readiness exercises, to increase actionable interoperability of health systems in Europe the US and globally, nurturing innovation and fuelling creativity with effective use of standards and interoperability