Operating with open innovation principles, ekip will establish a partner and network-driven policy recommendation engine to continuously drive the formulation and adoption of policy development recommendations for Europe’s Cultural and Creative Industries (CCIs). This will result in support and guidance that strengthens the capacity for CCI-actors to engage in and contribute to complex innovation processes. The interplay between the projects activities will allow us to deliver two objectives – building the meta-network amongst ecosystems and developing the knowledge-based and participatory policy engine – which will come together in making the third objective – supporting the development for CCI-centered ecosystems – possible. The engine is designed to in three main phases (i.e. five steps) achieve this: -Assess needs for future R&I actions - List of defined policy areas together with a meta-network of networks covering all member states and the CCI diversity. -Mapping of needs CCIs; tech, invest, skill, regulation - Investigate prioritised policy areas looking broadly and across sectors, also focusing on recommendations that will (i) increase the CCIs’ readiness for green and digital transitions as well as for the rest of the economy and society. -Identify and propose key actions - Formulate policy recommendations, also giving practical guidelines of how to implement and track development in ecosystems. ekip brings together highly networked and diverse organisations with strong track-record in research, innovation, and policymaking for and with the CCIs. Beneficiaries from 12 countries with different social, cultural, and economic contexts. Leading universities with expertise on research and innovation in culture and creativity. Organisations with online data collection and analysis competences and visualisation skills. Specialised policy consulting companies and advisories will be linking practice, research, and innovation with policy development for the CCI.

Additive manufacturing (AM) has been highlighted as a key technology with potential for creating sustainable high value European based employment, addressing societal issues and supporting environmental sustainability. It has the potential to revolutionize the way in which products are manufactured and delivered to the customer. Moreover, AM is already having a high economic impact on several sectors and indeed on wider society. Therefore, it challenges the community to reinvent the business models and explore the implications of AM adoption. All those are heavyweight reasons for Europe to make specific efforts to define a plan of action in the field. In this framework, AM-Motion CSA has the ambition to develop a strategy and set up the pillars for its efficient implementation that, ultimately, will contribute to reinforcing the European AM ecosystem. The project will accelerate market uptake of AM technologies across Europe by connecting and upscaling existing initiatives and efforts around defined value chains, improving the conditions for large-scale, cross-regional demonstration and market deployment, and by involving a large number of key stakeholders, particularly from industry, as experts. AM-Motion will identify gaps at technical and non-technical levels for business development and propose specific actions and including a timeline to overcome them. More importantly, it will propose and validate models for business collaboration and unlock AM based business and jobs for Europe. To involve high number of key actors, the project has already achieved the support of several companies, research and education establishments, standardisation bodies, European Technology Platforms, international AM related entities, Regions and Innovation clusters. 52 support letters were received and are included.

COOPERATE overall objective is to develop and pilot the ERA Hub concept based on the vision and success stories developed within the EuroTech Universities Alliance and their R&I ecosystems. The overall approach revolves around co-creation Arenas in which ecosystems and a broader community of quadruple helix actors can interact. The piloting phases of the project’s implementation are expected to test the approach and pave the way for its consolidation and replication phase. The approach follows a mechanism in which leverage is sought to engage a broad range of stakeholders, activate cross-fertilization, facilitate mutual understanding, create intertwining cooperation, and jointly develop innovative ideas for shaping the ERA Hub framework model for further piloting and validation. The intended ERA Hub model builds on lines of action (e.g. access to knowledge and talents) which gather a set of initiatives/projects to animate the actors and stakeholders and operate the ecosystem around common priorities (i.e. strategic multi-annual roadmap) which reflect the mission-based approach. In this framework the key exploitable results include: 1) The ERA Hub model and associated PLAYBOOK, TOOLBOX and PLATFORM with compliance criteria to develop the ERA Hubs network; 2); the Policy Recommendations and content from co-creation activities. The consortium is aware that the outcome of the project is supporting the EC roadmap towards the launch of ERA Hubs as flagship initiative in Europe to boost the ERA, beyond the scope of the project. Tailor made communication, dissemination and exploitation actions will therefore create awareness and engagement within regional ecosystems in EU, building consensus in a close dialogue with EU and national/regional institutions. In particular two large events will be organised in Brussels at mid-term and at the end of the project for consensus building on the project findings and policy recommendations.

In Europe about 75% of all neonatal deaths and 60% of all infant deaths occur in infants born preterm, and worldwide 450 neonatal deaths occur every hour. The number of preterm births is growing despite advances in medicine as more pregnancies are in the later age but also due to increasing environmental treats and lack of suitable treatments. In the LIFESAVER vision, every pregnant woman must have a proper living environment with the minimal risks to the fetus, safeguarded with scientifically justified regulations in use and control of potentially risky chemical and medicinal products, leading to healthier quality lives of the babies, overarching for generations. The LIFESAVER addresses the presently unmet societal and healthcare needs in creating and developing of a validated scientific knowledge base for the development and implementation of regulatory approaches relevant to maternal and fetal health. The objective is in creation of new, digitally cloned in vitro system for emulation of the pre-natal conditions in the vicinity of uterine/placental interface, capable of future high biofidelity prediction of safety and risk of substances towards unborn babies. LIFESAVER concept is based on an original idea of hybridization of several innovative technologies, integrating digital in silico/in vitro (biodigital twin) systems, enabling effective screening of chemicals and pharmaceuticals which might affect pregnant women health, reducing animal, preclinical and clinical testing, which is not presently possible with any other existing approaches to the same level of confidence. The outcomes are in design, manufacturing and deployment of a platform having key components of in vitro placental tissue for sufficient emulation of typical prenatal conditions. This aims to provide a solid scientific rationale for new regulations for chemical and pharmaceutical use relevant for the Green Deal vision.

DigiPrime has the mission to develop a new concept of Circular Economy digital platform overcoming current information asymmetry among value-chain stakeholders, in order to unlock new circular business models based on the data-enhanced recovery and re-use of functions and materials from high value-added post-use products with a cross-sectorial approach. DigiPrime will create and operate a federated model of digital platforms for cross-sector business in the Circular Economy. Nodes of the federation will offer interoperable functions and data, that can be accessed by other nodes, combined with local data and services, that are not exposed outside; connectors and open interfaces enable easy integration of new services, provided by third parties, that are not made accessible outside. Specific attention will be devoted to create trustable data sharing mechanisms, preserving the confidentiality of business-critical data. Security and sovereignity of information are guaranteed by IDSA (Industrial Data Space Association)-based solutions for on-demand and controlled sharing of data among organisations, regulated by smart contracts and tracked by block-chain. The services covers: i) the cross-sector value-Chains dimension (De- and remanufacturing oriented product information management, product co-creation, LCA-LCC for eco-design, demand-supply matching, sustainable value network and reverse logistics barriers identification and legislation support, etc.), ii) the operational dimension (rediction of product conditions, de-and remanufacturing decision support system, demand and supply forecasting, circular production planning and control, material testing and certificationetc). DigiPrime, will be thoroughly validated through 6 cross-sectorial pilots, further detailed in 20 use-cases covering 5 different European industrial sectors (automotive, renewable energy, electronics, textile, construction), and by additional pilots in new sectors, funded through an Open Call mechanism.