Start a new DMP in Loading
In the context of the growing interest in data-sharing in medicine, this project aims 1/ to perform systematic re-analyses of Randomised Controlled Trials (RCTs) in order to assess their reproducibility and 2/ to develop a tool to identify transparent and reproducible scientific practices. We will critically appraise all initiatives for data-sharing in medicine and identify all platforms that enable RCT data to be shared. A random sample of 62 RCTs will be selected and re-analysed. The results of these re-analyses will be compared with the results of the original analyses. The same method will be applied for all new drugs submitted to the European Medicine Agency in order to replicate results and to provide practical information for drug regulation. The impact of certain contextual factors on reproducibility will be explored. A scale for scoring the sharing and reproducibility of useful data will be developed. France is involved in the G7 initiative calling for open practices in Science. This project will provide empirical data on these practices and their usefulness.
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