BLOSSOM introduces a systemic approach that links public authorities (cities-regions) with private partners (e.g., banks, insurance companies and venture capitals) to cope with the disconnections and gaps related to the adoption of bankable transformative adaptation and mitigation measures. Starting from the Communities of Practice, we will set up Living Labs, i.e. collaborative environments in which citizens, experts and other stakeholders will have the possibility to test and hone the methodology and the technologies. Innovative financing and investing schemes will be tested and assessed for the adoption of the most promising bankable solutions. BLOSSOM will follow already proven co-creation/design processes (including local communities), as well as the adoption and further adjustment of technologies that use data and collective intelligence to perform ex-ante simulation on-going and ex-post assessment in collaborative environments (digital twins and dashboards). By using AI-based tools a draft business model including a visual chart with elements describing the value proposition, infrastructure, customers, and financial elements of each investing scheme will be generated, also identifying the best exploitation form based on the nature of the results and ownership structure (e.g., creation of spin-offs, products producing and selling, licensing of products/services, patenting, etc.). Once the best business model has been selected, a preliminary Business Plan will be developed with the industrial partners being the main contributors. The bankable solutions will be demonstrated in our Front Runner Cities (Birmingham, Lisbon and Kielce), which will test the methodology and make it available for replication up to the planning stage in the Replicating case studies (Regions of West-Vlaanderen and Alentejo, and cities of Parma and Aarhus.