BIOGEMSE aims to develop and manufacture bio-intelligent, sustainable, circular, and safe modular construction products to pioneer a new way of building in modern architecture. To achieve that, the project is built on 3 working fields: i) Circular and sustainable bio-based materials for Additive Manufacturing (AM) processes, expanding their opportunities in the construction sector, ii) production "biologisation" through highly flexible digital and robotised AM; and iii) manufacturing-enabled bio-intelligent product performance. In BIOGEMSE, green and circular mortars will be fine-tuned for the AM processes and generative AI tools will be employed to explore novel bio-mimicking structures. AM will provide the high level of flexibility and customization required, and BIOGEMSE will work on extending 3D printing systems capabilities (at HW and SW levels) targeting bio-intelligent performance. At HW level, a novel robot printing head incorporating kinetics redundancy will be developed. At SW level, advanced monitoring and control tools will be integrated. Manufacturing will be further supported by process and products Digital Twins, simulation workflows, and AI-based decision support tools for Zero Defect Manufacturing. Moreover, a standardized and interoperable digital framework will be deployed, together with a Digital Product Passport, and environmental impact, circularity and safety will be considered through sound SSbD methodologies. The bio-intelligent modular structures will be deployed in 3 Smart Living Labs with different functional requirements and climatic conditions to validate the new products and boost their replication potential at EU-wide level. Technology-driven strategies will be complemented with the most adequate sustainable business models at global scale, and with a training strategy for professional skilling. To address this, BIOGEMSE gathers a competitive, industry-driven, multi-disciplinar, balanced and value-chain oriented consortium.