Powered by OpenAIRE graph
Found an issue? Give us feedback

DrugCer

Cold Sintering Process for Fabrication of Biodegradable Drug-Eluting Ceramics
Funder: European CommissionProject code: 101063841 Call for proposal: HORIZON-MSCA-2021-PF-01
Funded under: HE | HORIZON-TMA-MSCA-PF-EF Funder Contribution: 189,687 EUR
Description

DrugCer proposes a paradigm shift in drug delivery for bone restoration by making drugs an inherent part of a biodegradable ceramic implant. Such a new approach would require drug loading during ceramic sintering, which in turn requires multidisciplinary research and development of low-temperature/cold ceramic processing. Accordingly, the main research goal of DrugCer is to apply a novel pressure-assisted “Cold Sintering Process” (CSP) for co-sintering of biodegradable ceramics with drugs. To achieve the goal, the researcher will receive advanced training in CSP and develop the co-sintering process by establishing a relationship between the processing parameters and properties of the resulting bioceramics. She will train in and master cryo-focused ion beam milling and cryo-scanning transmission electron microscopy to investigate the process kinetics and densification mechanisms. Finally, she will train in and develop methods for complex shaping to adapt the method for potential translation to preclinical studies. Cold-sintering will decrease energy consumption in bioceramics’ fabrication. It will also enable bioceramic co-sintering with other temperature-sensitive materials (e.g., polymers), opening paths to innovations in fields beyond orthopedics or even medicine (e.g., construction ceramics). Multidisciplinary supervising teams at Fraunhofer IKTS (host) and Penn State University (secondment) will support training through research and transferrable skills development (grant writing, teaching/mentoring, project management, networking, and horizontal skills). Inter-sectoral communication with Charité hospital (short visits) will ensure high-quality guidance in developing prospective biomedical technology from its very beginning. Thus, DrugCer will equip the researcher with unique expertise, skills, and a professional network for establishing an independent group in the niche of low-temperature, energy-efficient ceramic processing.

Partners
Data Management Plans
Powered by OpenAIRE graph
Found an issue? Give us feedback

Do the share buttons not appear? Please make sure, any blocking addon is disabled, and then reload the page.

All Research products
arrow_drop_down
<script type="text/javascript">
<!--
document.write('<div id="oa_widget"></div>');
document.write('<script type="text/javascript" src="https://www.openaire.eu/index.php?option=com_openaire&view=widget&format=raw&projectId=corda_____he::d0e50d857bb74370e00771f232601f36&type=result"></script>');
-->
</script>
For further information contact us at helpdesk@openaire.eu

No option selected
arrow_drop_down