To reach its climate neutrality goals Europe needs to rely heavily on Power-to-X (PtX) technology to replace the many applications of fossil fuels that are not easily electrified. Many PtX technologies are however still immature or not ready for deployments yet, highlighting the need for a sustained R&D effort in the field. Neutron- and synchrotron sources can play a crucial role in this effort however lack of key instrumentation is limiting the current possibilities. ACTNXT will upgrade the instrumentation at current neutron- and synchrotron sources to enable it to provide crucial knowledge within PtX areas such as efficiency, safety, price, raw material consumption, and durability. This will be done by developing instrumentation for: 1. Operando measurements of processes and flow inside PtX components 2. Materials behaviour under hydrogen exposure 3. Reliable and high throughput investigation novel materials 4. Operando measurements hazardous chemical reactions The new instrumentation will be designed for broad adaptation as upgrades for many existing research instruments across Europe. Prototypes of all 4 instrumentation types will be constructed at leading research infrastructures and their capabilities tested and demonstrated. This is supplemented by a common knowledge platform addressing common challenges such safety and planning of complicated experiments. During the project the consortium will have a very strong dialogue with the user communities to ensure that the developed instrumentation matches its needs and that it is ready to take full advantage of the instrumentation also after the end of the project. In doing so ACTNXT aims to give the European green industry a huge boost and ensure that it captures a major part of an emerging trillion Euro PtX market.