Emergency Medical Services in Europe are characterised by a pluralistic landscape with diverse organisational setups, professional standards, coordination mechanisms and actors which result from different historical and institutional contexts in EU member states. However, diversity is united by the common aim, of providing timely care to victims of sudden and life-threatening injuries, emergencies or disasters within EU-member states (EUMS), in cross-border settings and international humanitarian missions. Fostering the response capacities and increasing the cooperation of the European Emergency Medical Services Systems (EMSS) is of decisive importance for strengthening the resilience of European societies in the light of multiple hazards: Climate change is increasing the frequency and severity of disasters, terrorism is becoming a very real scenario for mass causality events challenging both out-of-hospital as well as in-hospital emergency care, and health related hazards are calling for close cooperation of public safety and health authorities on an international level. Not only hazards but also the system’s diversity poses a challenge for preparedness planning and cooperation, which needs to involve the whole EMS system at regional and/or national level and integrate it into the whole health system and fully coordinate with the public safety system to be effective. The iProcureSecurity project seeks to identify the major challenges the system’s diversity poses to the ability to work together, stimulate R&I uptake with a view to increasing standardisation of operations across Europe, and deliver technical requirements for R&I activities to create a European system of Medical Emergency Teams that is more homogeneous and capable to work as singly unit. To achieve this aim, the project will engage in several exchange cycles with practitioners and other stakeholders in the innovation landscape as a preparation for major R&I activities as part of a PCP action.