The project aims to strengthen educational innovation in African higher education through the implementation of a sustainable and efficient network of institutions (6 African and 6 European ones) as well as experts in the development of MOOC (massive open online course) from Cameroon and Senegal. This network would promote access to higher education and improve teaching conditions and learning practices. To this end, the project targets the adoption of innovative educational practices, namely practices designed to substantially improve students’ learning, initially by teachers from partner institutions and in the long term by teachers outside the consortium through the development of MOOC and blended learning. Based on a one-year preliminary research which identified the needs of end users (Roland, Stavroulakis, François & Emplit, 2017), the project is structured around 5 areas: networking, institutional support, pedagogical support, technology development in line with the sub-Saharan African context and an iterative approach throughout continuous assessment. Therefore, the activities aim to develop, through partners, a network of excellence in terms of development and reuse of MOOC that will ultimately be able to transfer its expertise at an institutional and at a national level; to develop, by building capacities, support structures for innovative pedagogical practices within partner institutions; to produce technology solutions tailored to the African context for online and offline distribution of MOOC; to adopt a quality approach throughout the project in order to improve every step; to prepare and support the development of 14 MOOC (two national and two per institution); to promote blended learning practices and arouse an institutional reflection on how MOOC should be integrated in curricula and learners’ certification through these devices.