Staff in VET often lacks the skills and tools to address the career needs of learners. This was evidenced in recent projects implemented by the partners. Although there is an increasing recognition of the importance of education-business partnerships, there is little emphasis on the labour market and industry settings for these types of initiatives. There are also still several obstacles for young women and students with special learning needs who are interested in STEM careers. Our project aimed at several issues related to the low interest in STEM careers among young people. The proposal was made by a strong partnership of regional authority governing education (including VET) on the regional level - Zlínský kraj in the Czech Republic; VET providers - GRETB in Ireland, UTC in Italy; two enterprises with strong track record in VET and cooperation with companies – Trexima in the Czech Republic and SES13-19 Ltd. in the United Kingdom; CPIP - a centre for teachers training and supporting young people in Romania; and University of Cyprus bringing a great experience in the area of applying ICT tools to engage young people in STEM. We wanted to promote STEM careers among young people in a modern, interactive, and attractive way (with special attention to girls and young women and students with special education needs), to develop and strengthen cooperation between schools and companies in order to increase the quality of VET, to support young women and students with special learning needs to follow the career in STEM fields, and to reach the highest level of education possible and to upskill teachers and companies in work with talented students. In order to achieve these goals we organized two physical short-term joint staff training activities plus one online which, through observations, visits, seminars, discussions, and other methods, enabled exchange of know-how and presentation of best practice, contributed to up-skilling of the project target groups such as teachers, school leaders, and other school staff like career counsellors, Companies representatives, Chambers of Commerce, and Professional Associations representatives, Local, Regional and National Authorities with competence in Education, and also members of the academic staff at universities. These participants were actively involved in development and promotion of the project outputs - Training course for new STEM Supporters, Methodology for Teachers on Interactive, Attractive and Modern Ways of Engagement Young People in STEM Education and Publication with Proven and Suitable Strategies for Talents in STEM Support and Development. All project outputs were disseminated widely through existing promotional channels like the partners’ websites, national and local events related to STEM and VET education but mainly during the Final Conference, that was organized as a virtual activity due to the Covid pandemic issues. All partners are committed to maintain and update the project web site when the project is finished. All materials were produced in sufficient numbers for all partners to enable them to distribute these after the end of the project on seminars, meetings and conferences – this makes our project sustainable.