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Orchestration of long-range gene regulation by cohesin and transcription factors

Funder: Netherlands Organisation for Scientific Research (NWO)Project code: VI.C.222.049

Orchestration of long-range gene regulation by cohesin and transcription factors

Description

In our bodies genes need to be activated at the right time and the right place. Many of these genes are activated by pieces of DNA that are located far away in the genome. The folding of our genome plays an important role in the correct regulation of these genes. We will investigate which factors are important in this process. This will lead to a better understanding how genes are regulated during embryonal development and what happens in developmental disorders.

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