The goal of the HUMAN project is to provide the first systematic analysis on the cost of uncertainties related to the hydrogen-led decarbonisation of heat. Sustainable decarbonisation pathways require uncertainty-resilient policies. These policies can be informed by acknowledging proactively the uncertainties inflicted by technology performance, volatility in heat demand and socio-economic fluctuations. With the power sector becoming increasingly reliant on intermittent renewable sources and the Government's commitment to "Net-Zero" by 2050, the role of hydrogen towards heat decarbonisation and the related uncertainties need to be urgently explored. The project considers strategic and operational decisions related to the deployment of a hydrogen-led system and its interaction with the power grid across multiple spatial and temporal scales. Employing the tools developed within the project the optimal mix of electrification and hydrogen-based decarbonisation of heat will be explored at a UK-wide level. Using novel uncertainty modelling methods, the impact of uncertainties related to the heat sector and the hydrogen production technologies will be analysed to derive uncertainty-informed transition pathways. Finally, HUMAN proposes to disseminate an open-source platform with user-friendly interface to enhance interpretability among energy policy practitioners and enable the investigation of alternative uncertainty-informed scenarios for heat decarbonisation.