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Cell
Article . 2004
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MicroRNAs: genomics, biogenesis, mechanism, and function.

Authors: Bartel, David P;

MicroRNAs: genomics, biogenesis, mechanism, and function.

Abstract

MicroRNAs (miRNAs) are endogenous approximately 22 nt RNAs that can play important regulatory roles in animals and plants by targeting mRNAs for cleavage or translational repression. Although they escaped notice until relatively recently, miRNAs comprise one of the more abundant classes of gene regulatory molecules in multicellular organisms and likely influence the output of many protein-coding genes.

Keywords

Genome, Base Sequence, Transcription, Genetic, Molecular Sequence Data, Models, Biological, MicroRNAs, Phenotype, Species Specificity, Protein Biosynthesis, Animals, Humans, Drosophila, RNA, Small Interfering, Caenorhabditis elegans, Plant Proteins

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    influence
    This indicator reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
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selected citations
These citations are derived from selected sources.
This is an alternative to the "Influence" indicator, which also reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
BIP!Citations provided by BIP!
popularity
This indicator reflects the "current" impact/attention (the "hype") of an article in the research community at large, based on the underlying citation network.
BIP!Popularity provided by BIP!
influence
This indicator reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
BIP!Influence provided by BIP!
impulse
This indicator reflects the initial momentum of an article directly after its publication, based on the underlying citation network.
BIP!Impulse provided by BIP!
30K
Top 0.01%
Top 0.01%
Top 0.01%