The challenge of the DURACELL project is to improve the durability of PEM fuel cells by optimizing the mechanical properties of the interfaces within the membrane-electrode assemblies (MEAs), where the electrochemical reactions take place. The latter are subjected to complex and variable mechanical stresses depending on the hygrothermal conditions related to the operation of the fuel cell, which can lead to the damage of its components and the shutdown of the system. The initial objective of the project will be to measure, identify and control the manufacturing parameters of the MEA that impact the adhesion between its layers. To that goal, specific mechanical characterizations will be implemented in order to quantify the level of adhesion at the interfaces of MEAs manufactured within the DURACELL project consortium. The measured properties will then be implemented in a numerical model in order to contribute to the prediction of the optimal physical properties of the MEA and its assembly conditions to limit the mechanical damage of its components. These results will be verified by comparing the lifetime of MEAs assembled under these different adhesion conditions, via in situ and ex situ accelerated stress tests (hygrothermal cycling and coupled mechanical/chemical degradation). These different tests will provide a better understanding of the mechanical/chemical degradation synergies that occur in the membrane and at the membrane|electrode|gas diffusion layers interfaces. They will also allow to unbundle the different mechanisms responsible for the degradation of MEAs in a system environment. The analysis of the results of the DURACELL project will lead to recommendations to be shared with the scientific and industrial community to limit the level of mechanical stresses undergone by the different components of a PEMFC, thus contributing to the increase of its life span in operation.